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Luke Chen

Luke Chen

Student Researcher | G6PD Advocate | Creator of G6PD.ai

My G6PD Journey

Luke Chen

I was diagnosed with G6PD deficiency as an infant when I experienced severe jaundice. Growing up, I learned to navigate a world full of hidden triggers—certain medications, foods like fava beans, and even some household chemicals could potentially cause dangerous hemolytic episodes.

My mother and sister also carry the G6PD gene, making this truly a family matter. This personal experience drove me to create G6PD.ai, the world's first AI-powered safety checker for G6PD patients. But I knew that managing triggers wasn't enough—I wanted to understand the science deeply enough to contribute to finding a cure.

Research Vision

Luke Chen - Research

My approach combines computational biology with emerging gene editing technologies. By studying G6PD protein structures through AlphaFold and exploring CRISPR-Cas9 therapeutic strategies, I'm working to bridge the gap between structural biology and clinical intervention.

This website documents my research journey and serves as a resource for others in the G6PD community. I believe that open science and collaboration are key to accelerating breakthroughs in rare disease research.

Background & Credentials

G6PD Researcher
Computational Biology Focus
AlphaFold Certified
DeepMind & EMBL-EBI
G6PD.ai Creator
AI Safety Checker App
Bioethics Study
Gene Therapy Ethics

Research Timeline

2025
Launched G6PD.ai
Created the world's first AI-powered safety checker for G6PD patients, helping thousands check medication and food safety.
2025
AlphaFold Structure Analysis
Began systematic analysis of G6PD protein structure using AlphaFold predictions to understand variant impacts.
2025
Molecular Dynamics Research
Started running computational simulations to study how mutations affect G6PD stability and function over time.
2025
Variant Database
Built a comprehensive database cataloging 217+ known G6PD mutations with WHO classifications, structural locations, and clinical severity data.
2025
CRISPR Therapeutics
Exploring CRISPR-Cas9 and base editing strategies to correct G6PD mutations in hematopoietic stem cells, inspired by the FDA-approved Casgevy therapy for sickle cell disease.
Future
Experimental Validation
Goal to collaborate with research labs to experimentally validate computational predictions and advance toward therapeutic development.

Let's Connect

Whether you're a researcher, clinician, or fellow G6PD patient, I'd love to hear from you.

Email Me Join Community