Exploring computational biology approaches to understand and potentially cure the world's most common enzyme deficiency.
Explore the 3D structure of Glucose-6-phosphate dehydrogenase predicted by AlphaFold
G6PD is a homodimeric enzyme that catalyzes the first step of the pentose phosphate pathway. The protein consists of 515 amino acids and requires NADP+ as a structural cofactor for stability.
A comprehensive computational approach to understanding and treating G6PD deficiency
3D protein structure prediction and variant impact analysis
Simulating protein behavior and mutation effects over time
Comprehensive mapping of 217+ known G6PD mutations
Drug safety analysis and oxidative stress mechanisms
AI-powered search for therapeutic compounds
Gene editing approaches for potential cure
Stay updated on the latest G6PD research breakthroughs and contribute to advancing our understanding of this condition.